Important Notes : No G2CET Lateral Entry Test from 2015. Goa Lateral Entry 2015 Admission based on Qualifying Exam Score.

G2CET 2015 Syllabus for Pharmacy

G2CET Syllabus for Direct Second Year B.Pharm Admissions

Pharmacology & Toxicology

1. Routes of administration of drugs.

2. Drug transport, absorption, metabolism & excretion.

3. Sedatives & hypnotics; Antianxiety drugs; Anti depressants; Narcotic analgesics; NSAIDS.

4. Pharmacology of acetylcholine, Atropine and Anticholinesterase drugs.

5. Phamacology of Adrenergic drugs & Adrenergic receptor blockers.

6. Drugs used to treat CHF, Angina & Hypertension.

7. Diuretics and anti diuretics.

8. Purgatives; Antidiarrhoeals; Antiemetics drugs used to treat peptic ulcer.

9. Chemotherapy of TB, malaria, fungal and viral infections.

Pharmaceutical Chemistry II

Antiseptics and Disinfectants – Proflavine, Benzalkoniumchloride, Cetrimide, Chlorocresol, Chloroxylene, Formaldehyde solution, Hexachlorophene, Liquified phenol, Nitrofurantoin. Sulfonamides – Sulfadiazine, Sulfaguanidine, Phthalysulfathiazole, Succinylsulfathiazole, Sulfadimethoxine, Sulfamethoxypridazine, Sulfamethoxazole, co – trimoxazole, Sulfacetamide.

Anti – tubercular Drugs – Isoniazid, PAS, Streptomycin, Rifampicin, Ethambutol, Thiacetazone, Ethionamide, Cycloserine, Pyrazinamide. Antiamoebic and Anthelmintic Drugs – Emetine, Metronidazole, Halogenated hydroxyquinolines, diloxanidefuroate, Paramomycin Piperazine, Mebendazole, D.E.C,. Antibiotics – Benzyl Penicillin, Phenoxy methyl Penicillin, Benzathine Penicillin Ampicillin, Cloxacillin, Carbenicillin, Gentamicin, Neomycin, Erythromycin, Tetracycline, Cephalexin, Cephaloridine, Cephalothin, Griseofulvin, Chloramphenicol.

Antimalarial Drugs – Chloroquine, Amodiaquine, Primaquine, Proguanil, Pyrimethamine, Quinine, Trimethoprim. Tranquilizers – Chlorpromazine, Prochlorperazine, TrifluoPerazine, Thiothixene, Haloperidol, Triperidol, Oxypertine, Chlordiazepoxide, Diazepam, Lorazepam, Meprobamate. Hypnotics – Phenobarbitone, Butobarbitone, Cyclobarbitone, Nitrazepam, Glutethimide, Methyprylone, Paraldehyde, Triclofos sodium.

Antidepressant Drugs – Amitriptyline, Nortryptyline, Imipramine, Phenelzine, Tranylcypromine. Analeptics – Theophylline, Caffeine, Coramine, Dextroamphetamine. Adrenergic Drugs – Adrenaline, Noradrenaline, Isoprenaline, Phenylephrine Salbutamol, Terbutaline, Ephedrine, Pseudoephedrine. Adrenergic Antagoinst – Tolazoline, Propranolol, Practolol.

Cholinergic Drugs – Neostigmine, Pyridostigmine, Pralidoxime, Pilocarpine, Physostigmine. Cholinergic Antagonists – Atropine, Hysocine, Homatropine, Propantheline, Benztrophine, Tropicamide, Biperiden. Diuretic Drugs – Furosemide, Chlorothiazide, Hydrochlorothaizide, Benzthiazide, Urea, Mannitol , Ethacrynic Acid. Cardiovascular Drugs – Ethyl nitrite, Glyceryl trinitrate. Hypoglycemic Agents – Insulin, Chlorpropamide, Tolbutamide, Glibenclamide, Phenformin , Metformin.

Local Anaesthetics – Lignocaine, Procaine, Benzocaine. Histamine and Anti – histaminic Agents – Histamine, Diphenhydramine, Promethazine, Cyproheptadine, Mepyramine, Pheniramine, Chlorpheniramine. Analgesics and Anti – pyretics – Morphin, Pethidine, Codeine, Methadone, Aspirin, Paracetamol, Analgin, Dextropropoxyphene, Pentazocine. Non – steroidal anti – inflammatory Agents – Indomethacin, phenylbutazone, Oxyphenbutazone, Ibuprofen, Thyroxine and Antithyroids – Thyroxine, Methimazole, Methylthiouracil, Propylthiouracil.

Steroidal Drugs – Betamethazone, Cortisone, Hydrocortisone, prednisolone, Progesterone, Testosterone, Oestradiol, Nandrolone. Anti – Neoplastic Drugs – Actinomycins, Azathioprine, Busulphan, Chlorambucil, Cisplatin cyclophosphamide, Daunorubicin hydrochloride, Fluorouracil, Mercaptopurine, Methotrexate, Mytomycin.

Pharmaceutics II

1. Dispensing Pharmacy :

  • Prescriptions – Reading and understanding of prescription; Latin terms commonly used ( Detailed study is not necessary ), Modern methods of prescribing, adoption of metric system. Calculations involved in dispensing.
  • Incompatibilities in Prescriptions – Study of various types of incompatibilities – physical, chemical and therapeutic.

2. Dispensed Medications :

( Note : A detailed study of the following dispensed medication is necessary. Methods of preparation with theoretical and practical aspects, use of appropriate containers and closures. Special labelling requirements and storage conditions should be high – lighted ).

i ) Powders – Types of powders – Advantages and disadvantages of powders, Granule, Cachets and Tablet triturates. Preparation of different types of powders encountered in prescriptions. Weighing methods, possible errors in weighing, minimum weighable amounts and weighing of material below the minimum weighable amount, geometric dilution and proper usage and care of dispensing balance.

ii ) Liquid Oral Dosage Forms :

a) Monophasic – Theoretical aspects including commonly used vehicles, essential adjuvant like stabilizers, colourants and flavours, with examples.

Review of the following monophasic liquids with details of formulation and practical methods.

  • Liquids for internal administration – Liquids for external administration or used on mucus membranes.
  • Mixtures and concentrates – Gargles.
  • Syrups – Mouth washes Throat – paints Douches.
  • Elixirs – Ear Drops Nasal drops & Sprays Liniments Lotions.

b) Biphasic Liquid Dosage Forms :

i) Suspension ( elementary study ) – Suspensions containing diffusible solids and liquids and their preparations. Study of the adjuvants used like thickening agents, wetting agents, their necessity and quantity to be incorporated. Suspensions of precipitate forming liquids like,tinctures, their preparations and stability. Suspensions produced by chemical reaction. An introduction to flocculated, non – flocculated suspension system.

ii) Emulsions – Types of emulsions, identification of emulsion system, formulation of emulsions, selection of emulsifying agents. Instabilities in emulsions. Preservation of emulsions.

iii) Semi – Solid Dosage Forms :

a) Ointments – Types of ointments, classification and selection of dermatological vehicles.

Preparation and stability of ointments by the following processes :

  • Trituration.
  • Fusion.
  • Chemical reaction.
  • Emulsification.

Pastes – Difference between ointments and pastes, bases of pastes. Preparation of pastes and their preservation. Jellies – An introduction to the different types of jellies and their preparation. An elementary study of poultice.

Suppositories and pessaries – Their relative merits and demerits, types of suppositories, suppository bases, classification, properties, Preparation and packing of suppositories. Use of suppositories for drug absorption.

iv ) Dental and Cosmetic Preparations :

Introduction to Dentrifices, Facial cosmetics, Deodorants, Antiperspirants, Shampoos, Hair dressing and Hair removers.

v ) Sterile Dosage Forms :

  • Parenteral dosage forms – Definitions, General requirements for parenteral dosage forms. Types of parenteral formulations, vehicles, adjuvants, processing, personnel, facilities and Quality control. Preparation of Intravenous fluids and admixtures – Total parenteral nutrition, Dialysis fluids.
  • Sterility testing, Particulate matter monitoring – Faulty seal packaging.
  • Ophthalmic Products – Study of essential characteristics of different ophthalmic preparations. Formulation additives, special precautions in handling and storage of ophthalmic products.

Hospital and Clinical Pharmacy

Part – I : Hospital Pharmacy :

1. Hospital Pharmacy :

  • Definition
  • Functions and objectives of Hospital Pharmaceutical services.
  • Location, Layout, Flow chart of material and men.
  • Personnel and facilities requirements including equipments based on individual and basic needs.
  • Requirements and abilities required for Hospital pharmacists.

2. Drug Distribution system in Hospitals :

a. Out – patient services
b. In – patient services

  • Types of services
  • Detailed discussion of unit Dose system, Floor ward stock system, Satellite pharmacy services, Central sterile services, Bed Side Pharmacy.

3. Nomenclature and uses of surgical instruments and Hospital Equipments and health accessories.

4. P.T.C ( Pharmacy Therapeutic Committee ), Hospital Formulary System and their organisation, functioning, composition.

5. Drug Information service and Drug Information Bulletin.

6. Surgical dressing like cotton, gauze, bandages and adhesive tapes including their pharmacopoeial tests for quality. Other hospital supply e.g I.V sets B.G sets, Ryals tubes, Catheters, Syringes etc.

7. Application of computer in maintenance of records, inventory control, medication monitoring, drug information and data storage and retrieval in hospital and retail pharmacy establishments.

PART – II : Clinical Pharamacy

1. Introduction to Clinical Pharmacy Practice – Definition, scope.

2. Modern dispensing aspects – Pharmacists and Patient counselling and advice for the use of common drugs, medication history.

3. Common daily terminology used in the Practice of Medicine.

4. Disease, manifestation and pathophysiology including salient symptoms to understand the disease like : Tuberculosis, Hepatitis, Rheumatoid Arthritis, Cardiovascular diseases, Epilepsy, Diabetes, Peptic, Ulcer and Hypertension.

5. Physiological parameters with their significance.

6. Drug Interactions :

  • Definition and introduction.
  • Mechanism of Drug Interaction.
  • Drug – drug interaction with reference to analgesics, diuretics, cardiovascular drugs, Gastro – intestinal agents, Vitamins and Hypoglycemic agents.
  • Drug – food interaction.

7. Adverse Drug Reactions :

  • Definition and Significance.
  • Drug – induced diseases and Teratogenicity.

8. Drugs in Clinical Toxicity – Introduction, general treatment of poisoning, systematic antidotes. Treatment of insecticide poisoning, heavy metal poison, Narcotic drugs, arbiturate, Organophosphorous poisons.

9. Drug dependences, Drug abuse, addictive drugs and their treatment, complications.

10. Bio – availability of drugs, including factors affecting it.

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