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**Manipal University Syllabus 2018**

Manipal University test papers in **Physics, Chemistry, Biology, Mathematics and General English** includes questions based on the 10+2 syllabus followed by major 10+2 Boards / Universities.

## MU OET Physics Syllabus 2018

**Manipal University Physics Syllabus 2018**

**Units and Measurement **

Need for measurement: Units of measurement; systems of units; SI units, fundamental and derived units. Length, mass and time measurements; accuracy and precision of measuring instruments; errors in measurement; significant figures. Dimensions of physical quantities, dimensional analysis and its applications

**Kinematics**

Frame of reference, Motion in a straight line: Position-time graph, speed and velocity. Elementary concepts of differentiation and integration for describing motion, uniform and non-uniform motion, average speed and instantaneous velocity, uniformly accelerated motion, velocity – time and position-time graphs. Relations for uniformly accelerated motion (graphical treatment). Scalar and vector quantities; position and displacement vectors, general vectors and their notations; equality of vectors, multiplication of vectors by a real number; addition and subtraction of vectors, relative velocity, Unit vector; resolution of a vector in a plane, rectangular components, Scalar and Vector product of vectors. Motion in a plane, cases of uniform velocity and uniform acceleration-projectile motion, uniform circular motion.

**Laws of Motion**

Intuitive concept of force, Inertia, Newton’s first law of motion; momentum and Newton’s second law of motion; impulse; Newton’s third law of motion. Law of conservation of linear momentum and its applications. Equilibrium of concurrent forces, Static and kinetic friction, laws of friction, rolling friction, lubrication. Dynamics of uniform circular motion: Centripetal force, examples of circular motion (vehicle on a level

circular road, vehicle on a banked road).

**Work and Energy**

Work done by a constant force and a variable force; kinetic energy, work-energy theorem, power. Notion of potential energy, potential energy of a spring, conservative forces; conservation of mechanical energy ( kinetic and potential energies ) ; non-conservative forces; motion in a vertical circle, elastic and inelastic collisions in one and two dimensions.

**Motion of System of Particles and Rigid Body**

Centre of mass of a two-particle system, momentum conservation and centre of mass motion. Centre of mass of a rigid body; centre of mass of uniform rod. Moment of a force, torque, angular momentum, conservation of angular momentum with some examples. Equilibrium of rigid bodies, rigid body rotation and equation of rotational motion, comparison of linear and rotational motions; moment of inertia, radius of gyration. Values of moment of inertia for simple geometrical objects. Parallel and perpendicular axes theorems and their applications.

**Gravitation**

Kepler’s laws of planetary motion, universal law of gravitation. Acceleration due to gravity and its variation with altitude and depth. Gravitational potential energy and gravitational potential, escape velocity, orbital velocity of a satellite, Geo-stationary satellites.

**Properties of Matter**

Elastic behaviour, Stress-strain relationship, Hooke’s law, Young’s modulus, bulk modulus, shear modulus of rigidity, Poisson’s ratio; elastic energy. Pressure due to a fluid column; Pascal’s law and its applications (hydraulic lift and hydraulic brakes), effect of gravity on fluid pressure. Viscosity, Stokes’ law, terminal velocity, streamline and turbulent flow, critical velocity, Bernoulli’s theorem and its applications. Surface energy and surface tension, angle of contact, excess of pressure across a curved surface, application of surface tension ideas to drops, bubbles and capillary rise. Heat, temperature, thermal expansion; thermal expansion of solids, liquids and gases, anomalous expansion of water; specific heat capacity; Cp, Cv – calorimetry; change of state – latent heat capacity. Heat transfer-conduction, convection and radiation, thermal conductivity, qualitative ideas of Blackbody radiation, Wien’s displacement Law, Stefan’s law, and Greenhouse effect.

**Thermodynamics**

Thermal equilibrium and definition of temperature. Heat, work and internal energy. First law of thermodynamics. Isothermal and adiabatic processes. Second law of thermodynamics : Reversible and irreversible processes. Heat engines and refrigerators.

**Behaviour of Perfect Gases and Kinetic Theory of Gases**

Equation of state of a perfect gas, work done in compressing a gas. Kinetic theory of gases – assumptions, concept of pressure. Kinetic interpretation of temperature; rms speed of gas molecules; degrees of freedom, law of equi-partition of energy (statement only) and application to specific heat capacities of gases; concept of mean free path, Avogadro’s number.

**Oscillations and Waves**

Periodic motion – time period, frequency, displacement as a function of time, periodic functions. Simple harmonic motion (S.H.M) and its equation; phase; oscillations of a loaded spring-restoring force and force constant; energy in S.H.M. Kinetic and potential energies; simple pendulum derivation of expression for its time period. Free, forced and damped oscillations (qualitative ideas only), resonance.Wave motion: Transverse and longitudinal waves, speed of wave motion, displacement relation for a progressive wave, principle of superposition of waves, reflection of waves, standing waves in strings and organ pipes, fundamental mode and harmonics, Beats, Doppler effect

**Electrostatics**

Electric Charges; Conservation of charge, Coulomb’s law-force between two point charges, forces between multiple charges; superposition principle and continuous charge distribution. Electric field, electric field due to a point charge, electric field lines, electric dipole, electric field due to a dipole, torque on a dipole in uniform electric field. Electric flux, statement of Gauss’s theorem and its applications to find field due to infinitely long straight wire, uniformly charged infinite plane sheet and uniformly charged thin spherical shell ( field inside and outside ). Electric potential, potential difference, electric potential due to a point charge, a dipole and system of charges; equipotential surfaces, electrical potential energy of a system of two point charges and of electric dipole in an electrostatic field. Conductors and insulators, free charges and bound charges inside a conductor. Dielectrics and electric polarisation, capacitors and capacitance, combination of capacitors in series and in parallel, capacitance of a parallel plate capacitor with and without dielectric medium between the plates, energy stored in a capacitor.

**Current Electricity **

Electric current, flow of electric charges in a metallic conductor, drift velocity, mobility and their relation with electric current; Ohm’s law, electrical resistance, V-I characteristics (linear and non-linear), electrical energy and power, electrical resistivity and conductivity, Carbon resistors, colour code for carbon resistors; series and parallel combinations of resistors; temperature dependence of resistance. Internal resistance of a cell, potential

difference and emf of a cell, combination of cells in series and in parallel, Kirchhoff’s laws and simple applications, Wheatstone bridge, metre bridge. Potentiometer – principle and its applications to measure potential difference and for comparing EMF of two cells; measurement of internal resistance of a cell

**Magnetic Effects of Current and Magnetism**

Concept of magnetic field, Oersted’s experiment. Biot – Savart law and its application to current carrying circular loop. Ampere’s law and its applications to infinitely long straight wire, straight and toroidal solenoids. Force on a moving charge in uniform magnetic and electric fields. Cyclotron. Force on a current-carrying conductor in a uniform magnetic field. Force between two parallel current carrying conductors – definition of ampere. Torque experienced by a current loop in a magnetic field; moving coil galvanometer – its current sensitivity and conversion to ammeter and voltmeter. Current loop as a magnetic dipole and its magnetic dipole moment. Magnetic dipole moment of a revolving electron. Magnetic field intensity due to a magnetic dipole ( bar magnet ) along its axis and perpendicular to its axis. Torque on a magnetic dipole ( bar magnet ) in a uniform magnetic field; bar magnet as an equivalent solenoid, magnetic field lines; Earth’s magnetic field and magnetic elements. Para-, dia- and ferro – magnetic substances, with examples. Electromagnets and factors affecting their strengths. Permanent magnets.

**Electromagnetic Induction and Alternating Currents**

Electromagnetic induction; Faraday’s laws, induced EMF and current; Lenz’s Law, Eddy currents. Self and mutual induction. Alternating currents, peak and RMS value of alternating current/voltage; reactance and impedance; LC oscillations (qualitative treatment only), LCR series circuit, resonance; power in AC circuits, power factor, wattless current. AC generator and transformer

**Electromagnetic Waves**

Basic idea of displacement current, Electromagnetic waves, their characteristics, their Transverse nature (qualitative ideas only). Electromagnetic spectrum (radio waves, microwaves, infrared, visible, ultraviolet, Xrays, gamma rays) including elementary facts about their uses.

**Optics**

Ray Optics: Reflection of light, spherical mirrors, mirror formula, refraction of light, total internal reflection and its applications, optical fibres, refraction at spherical surfaces, lenses, thin lens formula, lens maker’s formula, magnification, power of a lens, combination of thin lenses in contact, refraction and dispersion of light through a prism. Scattering of light – blue colour of sky and reddish appearance of the sun at sunrise and sunset. Optical instruments: Microscopes and astronomical telescopes (reflecting and refracting) and their magnifying powers. Wave optics: Wave front and Huygen’s principle, reflection and refraction of plane wave at a plane surface using wave fronts. Proof of laws of reflection and refraction using Huygen’s principle. Interference, Young’s double slit experiment and expression for fringe width, coherent sources and sustained interference of light, diffraction due to a single slit, width of central maximum, resolving power of microscope and astronomical telescope, polarisation, plane polarised light, Brewster’s law, uses of plane polarised light and Polaroids.

**Dual Nature of Radiation and Matter**

Dual nature of radiation, Photoelectric effect, Hertz and Lenard’s observations; Einstein’s photoelectric equation-particle nature of light. Matter waves-wave nature of particles, de-Broglie relation, Davisson-Germer experiment (experimental details should be omitted; only conclusion should be explained).

**Atoms and Nuclei**

Alpha-particle scattering experiment; Rutherford’s model of atom; Bohr model, energy levels, hydrogen spectrum. Composition and size of nucleus, Radioactivity, alpha, beta and gamma particles / rays and their properties; radioactive decay law. Mass-energy relation, mass defect; binding energy per nucleon and its variation with mass number; nuclear fission, nuclear fusion.

**Electronic Devices**

Energy bands in conductors, semiconductors and insulators ( qualitative ideas only ) Semiconductor diode – IV characteristics in forward and reverse bias, diode as a rectifier; Special purpose p-n junction diodes : LED, photodiode, solar cell and Zener diode and their characteristics, zener diode as a voltage regulator. Junction transistor, transistor action, characteristics of a transistor and transistor as an amplifier ( common emitter configuration ), basic idea of analog and digital signals, Logic gates ( OR, AND, NOT, NAND and NOR ).

**Communication Systems**

Elements of a communication system ( block diagram only ); bandwidth of signals ( speech, TV and digital data ); bandwidth of transmission medium. Propagation of electromagnetic waves in the atmosphere, sky and space wave propagation, satellite communication. Need for modulation, amplitude modulation.

**Experimental Skills**

- Familiarity with the basic approach and observations of the experiments and activities:
- Experiments based on use of vernier calipers and micrometer screw gauge
- Determination of g using simple pendulum
- Young’s modulus by Searle’s method
- Specific heat of a liquid using calorimeter
- Focal length of a concave mirror and a convex lens using uv-method
- Speed of sound using resonance column
- Verification of Ohm’s law using voltmeter and ammeter,
- Specific resistance of the material of a wire using Meter Bridge and post office box.

## MU OET Chemistry Syllabus 2018

**Manipal University Chemistry Syllabus 2018**

**Section-A : Physical Chemistry**

**1. Basic concepts in Chemistry** : Matter and its nature, Dalton’s atomic theory, concept of atom, molecule, element and compound. Laws of chemical combination, Atomic and molecular masses, mole concept and Avogadro number, molar mass, vapour density-definition. Relationship between molecular mass and vapour density. Concept of STP conditions, gram molar volume, percentage composition, empirical and molecular formulae, chemical equations and numerical problems in all these concepts, stoichiometry.

**2. States of matter :** Classification of matter – Solid, liquid and gaseous states

**Gaseous state** : Gas laws – Boyle’s law, Charles’s law, Graham’s law of diffusion, Avogadro’s law, Dalton’s law of partial pressures, Gay Lussac’s Law of combining volumes, concept of absolute temperature scale, Ideal gas equation, kinetic theory of gases – postulates, concept of average, root mean square and most probable velocities, Expressions for r.m.s velocity and kinetic energy from the kinetic gas equation. Numerical problems. Ideal and real gases, Ideal gas equation, value of R ( SI units ) . Deviation of real gases from the ideal behaviour. PV-P curves. Causes for the deviation of real gases from ideal behavior. Derivation of Van der Waal’s equation and interpretation of PV-P curves

**Liquid state** : Properties of liquids – vapour pressure, viscosity and surface tension, effect of temp. on them.

**Solid state** : classifications of solids : molecular, ionic, covalent and metallic solids, amorphous and crystalline solids, Bragg’s law and its applications, Unit cell and lattices, packing in solids ( fcc, bcc and hcp lattices ) voids, calculations involving unit cell parameters, imperfection in solids, electrical and magnetic properties. Band theory of metals, conductors, semiconductors and insulators and n & p type semiconductors.

**3. Atomic structure**

Introduction – Constituents of atoms, their charge and mass. Atomic number and atomic mass. Wave nature of light, Electromagnetic spectrum-emission spectrum of hydrogen-Lyman series, Balmer series, Paschen series, Brackett series and Pfund series. Rydberg’s equation. Numerical problems involving calculation of wavelength and wave numbers of lines in the hydrogen spectrum. Atomic model- Bohr’s theory, ( derivation of equation for energy and radius not required ). Explanation of origin of lines in hydrogen spectrum. Limitations of Bohr’s theory. Dual nature of electron – distinction between a particle and a wave. de Broglie’s Theory. Matter-wave equation ( derivation ). Heisenberg’s uncertainty principle ( Qualitative ). Quantum numbers – n, l, m and s and their significance and inter relationships. Concept of orbital – shapes of s, p and d orbitals. Pauli’s exclusion principle and Aufbau principle. Energy level diagram and ( n+1 ) rule. Electronic configuration of elements with atomic numbers from 1 to 54, extra stability of half-filled and completely filled orbitals. Hund’s rule of maximum multiplicity.

**4. Chemical bonding and molecular structure** : Kossel – Lewis approach to chemical bond formation, concept of ionic and covalent bonds.

**Ionic bonding** : formation of ionic bonds, factors affecting the formation of ionic bonds, calculation of lattice enthalpy.

**Covalent bonding** : valence shell electron pair repulsion ( VSEPR ) theory and shapes of simple molecules, molecular orbital theory ( MOT ) – linear combination of atomic orbitals ( Qualitative approach ) , energy level diagram, rules for filling molecular orbitals, bonding and anti-bonding molecular orbitals, bond order, electronic configuration of H2, Li2 and O2 Non-existence of He2 and paramagnetism of O2.

**Metallic bonding** : Electron gas theory (Electron Sea model), definition of metallic bond.

**Hydrogen bonding **– inter and intra molecular, properties.

**5. Solutions : **Methods of expressing concentration of solutions – ppm, molarity, molality, normality, mole fraction, percentage ( by volume and wt. ) , Principles of volumetric analysis- standard solution, titrations and indicators-acid-base ( phenolphthalein and methyl orange ) and redox ( Diphenylamine ) numerical problems. Vapour pressure of solutions and Raoult’s law, Ideal and non-ideal solutions, colligative properties of dilute solutions – relative lowering of vapour pressure, depression of freezing point, elevation of boiling point, osmotic pressure, calculation of mol. wt of a solute using colligative properties, van’t Hoff factor and its significance.

**6. Equilibrium : **Meaning of equilibrium, concept of dynamic equilibrium.

**Equilibrium involving physical processes** : solid – liquid, liquid – gas and solid – gas equilibria, Henry’s law, general characteristics of equilibrium involving physical processes.

**Equilibrium involving chemical processes** : Law of chemical equilibrium, equilibrium constants ( Kpand Kc ) and their significance, significance of ∆G and ∆G” in chemical equilibria, factors affecting equilibrium, concentration, pressure, temp., effect of catalyst, Le Chatelier’s principle.

**Ionic equilibrium** : Electrolytes and non-electrolytes, ionization of electrolytes, Electrolysis -Faraday’s Laws of electrolysis, numerical problems. Arrhenius theory of electrolytic dissociation, Merits and limitations. Specific conductivity and molar conductivity – definitions and units. Strong and weak electrolytes with examples. Factors affecting the conductivity. Acid – Base theories ( Arrhenius, Bronsted-Lowry and Lewis ) and their limitations, acid-base equilibria, ionization constants, Strengths of Acids and Bases – dissociation constants of weak acids and weak bases. Ostwald’s dilution law for weak electrolytes ( eq. derivation ) – expression for hydrogen ion concentration of weak acid and hydroxyl ion concentration of weak base – numerical problems. Ionic product of water, pH concept and pH scale. pKa and pKb values – numerical problems. Buffers, types of buffers, mechanism of buffer action, Henderson’s equation for pH of a buffer ( derivation ) , preparation of buffers of required pH -numerical problems. Common ion effect, solubility, expression for Ksp of sparingly soluble salts of types AB, AB2. Relationship between solubility and solubility product of salts of types AB, AB2. Applications of common ion effect and solubility product in qualitative analysis, numerical problems.

**7. Redox reactions and Electrochemistry : **Electronic concept of oxidation and reduction, redox reactions, oxidation number, rules for assigning oxidation number, balancing of redox reactions, Electrode potential – Definition, factors affecting single electrode potential, Standard electrode potential, Nernst’s equation for calculating single electrode potential, construction of electro-chemical cells, Daniel cell, free energy change during cell reactions ( ∆G ) . Reference electrodes – Standard Hydrogen Electrode ( SHE ) – construction, use of SHE for determination of SRP of other single electrodes and pH of solutions, Limitations of SHE. Electrochemical series and its applications, galvanic and electrolytic cells, half-cell and cell reactions, emf of a galvanic cell and its measurement, Nernst eq. and its applications, working principles of dry cell, lead acid cell and H2-O2fuel cell.

**8. Chemical Kinetics : **Introduction, commercial importance of rate studies, Order of a reaction, factors deciding the order of a reaction-relative concentrations of the reactants and mechanism of the reaction. First order reaction – eq. for rate constant derivation, units. Half-life period, relation between half-life period and order of a reaction, numerical problems. Determination of the order of a reaction by the graphical and the Ostwald’s isolation method. Zero order, fractional order and pseudo first order reactions with illustrations. Effect of temperature on the rate of a reaction, temperature coefficient of a reaction. Arrhenius interpretation of the energy of activation and temperature dependence of the rate of reaction. Arrhenius Equation. Influence of catalyst on energy profile. Numerical problems on energy of activation.

**9. Surface chemistry **

**Adsorption :** Physisorption and chemisorption and their characteristics, factors affecting adsorption of gases on solids, Freundlich and Langmuir adsorption isotherms, adsorption from solutions

**Catalysis :** Homogeneous and heterogeneous, activity and selectivity of solid catalysts, enzyme catalysis and its mechanism.

**Colloids : **Introduction, colloidal system and particle sizes. Types of colloidal systems, Lyophilic and lyophobic sols, examples and differences. Preparation of sols by Bredig’s arc method and peptisation. Purification of sols – dialysis and electro dialysis. Properties of sols – Tyndall effect, Brownian movement electrophoresis, origin of charge, coagulation, Hardy and Schulze rule, Protective action of sols. Gold number, Gold number of gelatin and starch. Applications of colloids. Emulsions and their characteristics.

**10. Chemical thermodynamics : **Concepts of System and types of systems, surroundings, work, heat, energy, extensive and intensive properties, state functions. Spontaneous and non-spontaneous processes, criteria for spontaneity – tendency to attain a state of minimum energy and maximum randomness. First law of thermodynamics -internal energy and enthalpy, heat capacity and specific heat, measurement of ΔU and ΔH, Hess’s law of constant heat summation, enthalpy of bond dissociation, combustion, formation, atomization, sublimation, phase transition, ionization, solution and dilution. Entropy – a measure of randomness, change in entropy, unit of entropy. Entropy and spontaneity. Second law of thermodynamics, Gibbs’ free energy as a driving force of a reaction, Gibbs’ equation, prediction of feasibility of a process in terms of ∆G, standard free energy change and its relation to Kp. Numerical problems.

**Section – B : Inorganic Chemistry**

**11. Periodic properties : **Periodic table – periods and groups. Modern periodic law and present form of periodic table, s,p,d and f block elements, atomic radii ( Van der Waal and covalent ) and ionic radii, comparison of size of cation and anion with the parent atom, size of isoelectronic ions. Ionization energy, electron affinity, electronegativity- definition with illustrations, Fajan’s rules. Variations of atomic radius, ionization energy, electron affinity, electronegativity down the group and along the period and their interpretation.

**12. Principles and processes of metal extractions** : Modes of occurrence of elements in nature, minerals, ores, steps involved in the extraction of metals – concentration, reduction ( chemical and electrolytic ) and refining with reference to the extraction of Al, Cu, Zn and Fe. Thermodynamic and electrochemical principles involved in the extraction of metals.

**13. Hydrogen** : isotopes, preparation, properties and uses of hydrogen. Physical and chemical properties of water and heavy water, structure, preparation, reactions and uses of hydrogen peroxide, classification of hydrides – ionic, covalent and interstitial, hydrogen as a fuel.

**14. S-block elements :** general introduction, electronic configuration and general trends in physical and chemical properties of elements, anomalous properties of the first element of each group, diagonal relationships. Preparation and properties of NaOH and NaHCO3. Industrial use of lime, limestone, plaster of paris and cement, biological significance of Na, K, Mg and Ca.

**15. P-block elements** : General electronic configuration and general trends in physical and chemical properties of elements across the periods and groups, unique behavior of first element in each group.

**Group 13** : Preparation, properties and uses of boron and aluminum, structure, properties and uses of borax, boric acid, diborane, boron trifluride, aluminum chloride and alums.

**Group 14** : Tendency for catenation, structure, properties and uses of allotropes and oxides of carbon, silicon tetrachloride, silicates, zeolites and silicones.

**Group 15** : properties and uses of nitrogen and phosphorus, allotropic forms of phosphorus, preparation, properties, structure and uses of ammonia, nitric acid, phosphine and phosphorus halides ( PCl3, PCl5 ) , structures of oxides and oxoacids of nitrogen and phosphorus.

**Group 16** : Preparation, properties, structures and uses of ozone, allotropic forms of sulphur, preparation, properties, structure and uses of sulphuric acid, structures of oxoacids of sulphur.

**Group 17** : Preparation, properties and uses of hydrochloric acid, trends in the acidic nature of hydrogen halides, structures of interhalogen compounds and oxides and oxoacids of halogens.

**Group 18** : Occurrence and uses of noble gases, isolation of rare gases by Ramsay and Raleigh’s method and separation of individual gases from noble gas mixture ( Dewar’s charcoal adsorption method ) . Structures of fluorides and oxides of xenon.

**16. d and f block elements** : Transition elements, electronic configuration, occurrence and characteristics, general trends in properties of 3d series – electronic configurations, size, variable oxidation states, colour, magnetic properties, catalytic behaviour, complex formation, interstitial compounds and alloy formation. Preparation, properties and uses of K2Cr2O7 and KMnO4.

**Lanthanoids** : Electronic configuration, oxidation states and lanthanoid contraction.

**Actinoids** : Electronic configuration and oxidation states.

**17. Co-ordination compounds :** Werner’s theory – ligands, co-ordination number, denticity, chelation, IUPAC nomenclature of mononuclear co-ordination compounds, isomerism, bonding – valence bond approach. Importance of co-ordination compounds in qualitative analysis, extraction of metals and in biological systems.

**18. Environmental chemistry**

Environmental pollution – atmospheric, water and soil – Atmospheric pollution – tropospheric and stratospheric Tropospheric pollutants – gaseous pollutants : oxides of carbon, nitrogen and sulphur, hydrocarbons, their sources, harmful effects and prevention. Green house effect and global warming, acid rain.

Particulate pollutants – smoke, dust, smog, fumes, mist, their sources, harmful effects and prevention Stratospheric pollution – formation and breakdown of ozone, depletion of ozone layer, its mechanism and effects.

Water pollution – major pollutants such as pathogens, organic wastes and chemical pollutants, their harmful effects and prevention.

Soil pollution – major pollutants such as pesticides ( insecticides, herbicides and fungiecides ) their harmful effects and prevention.

Stratagies to control environmental pollution.

**Section – C : Organic Chemistry**

**19. Purification and characterization of organic compounds**

Purification : crystallization, sublimation, distillation, differential extraction and chromatography – principles and their applications Qualitative analysis – detection of nitrogen, sulphur, phosphorus and halogens Quantitative analysis – basic principles involved in the estimation of carbon, hydrogen, nitrogen, halogens, sulphur and phosphorus. Calculations of empirical formulae and molecular formulae, numerical problems in org. quantitative analysis.

**20. Basic principles of organic chemistry** : Tetravalency of carbon, shapes of simple molecules – hybridization ( s and p ) , classification of organic compounds based on functional groups, compounds containing halogens, oxygen, nitrogen and sulphur. Homologues series, isomerism – structural and stereoisomerism.

**Nomenclature** : covalent bond fission – homolytic and heterolytic, free radicals, carbocations and carbanions. Stability of carbocations and free radicals, electrophiles and nucleophiles.

**Electronic displacement in a covalent bond** : Inductive effect, electromeric effect, resonance and hyperconjugation

**Types of organic reactions** : Substitution, addition, elimination and rearrangement.

**21. Hydrocarbons** : classification, isomerism, IUPAC nomenclature, general methods of preparation, properties and reactions

**Alkanes :** conformers, Sawhorse and Newman projections of ethane, mechanism of halogenation of alkanes

**Alkenes :** Geometrical isomerism, mechanism of electrophilic addition, addition of hydrogen, halogens, water, hydrogen halides – Markownikoff’s and peroxide effect, ozonolysis and polymerization.

**Alkynes** : Acidic character, addition of hydrogen, halogens, water and hydrogen halides, polymerization.

**Aromatic hydrocarbons** : Nomenclature, benzene – structure and aromaticity, mechanism of electrophilic substitution, halogenation, nitration, Friedel – Craft’s alkylation and acylation, directive influence of functional group in mono-substituted benzene.

**22. Organic compounds containing halogens** : General methods of preparation, properties and reactions. Nature of C-X bond, mechanisms of substitution reactions, uses, environmental effects of chloroform, iodoform, freons and DDT.

**23. Organic compounds containing oxygen** : General methods of preparation, properties and reactions.

**Alcohols, Phenols and Ethers** :

**Alcohols** : Identification of primary, secondary and tertiary alcohols, mechanism of dehydration

**Phenols** : Acidic nature, electrophilic substitution reactions, halogenation, nitration and sulphonation, Reimer – Tiemann reaction.

**Ethers** : Structures

**Aldehyde and Ketones** : Nature of carbonyl group, nucleophilic addition to >C=O group, relative reactivities of aldehydes and ketones, important reactions such as nucleophilic addition ( addition of HCN, NH3 and its derivatives ) , Grignard reagents, oxidation, reduction ( Wolf Kishner and Clemmnesen ) , acidity of α–hydrogen, aldol condensation, Cannizzaro reaction, Haloform reaction, chemical tests to distinguish between aldehydes and ketones.

**Carboxylic acids** : Acidic strength and factors affecting it.

**24. Organic compounds containing Nitrogen** : General methods of preparation, properties, reactions and uses.

**Amines** : Nomenclature, classification, structure, basic character and identification of primary, secondary and tertiary amines.

**Diazonium salts** : importance in synthetic organic chemistry

**25. Polymers** : General introduction and classification of polymers, general methods of polymerization – addition and condensation, copolymerization, natural and synthetic rubber and vulcanization, some important polymers with emphasis on their monomers and uses – polyethylene, nylon 6,6; polyester and bakelite.

**26. Biomolecuels** : general introduction and importance of biomolecules

**Carbohydrates : **Classification – aldoses and ketoses, monosaccharides ( glucose and fructose ) and constituent monosaccharides of oligosaccharides ( sucrose, lactose and maltose )

**Proteins : **Elementary idea of amino acids, peptide bond, polypeptide, proteins – primary, secondary, tertiary and quaternary, denaturation of proteins, enzymes**.**

**Vitamins : **Classification and functioning

**Nucleic acids – **chemical constitution of DNA and RNA, biological functions of nucleic acids.

**27. Chemistry in everyday life**

**Chemicals in medicine – **Analgesics, tranqilizers, antiseptics, disinfectants, antimicrobials, antifertility drugs, antibiotics, antacids, antihistamins – their meaning and common examples

**Chemicals in food – **Preservatives, artificial sweetening agents, common examples

**Cleansing agents – **Soaps and detergents, cleansing action

**28. Principles related to practical chemistry**

Detection of extra elements ( N, S, halogens ) in organic compounds, detection of the functional groups – hydroxyl ( alcoholic and phenolic ) , carbonyl ( aldehyde and ketone ) , carboxyl and amino groups in organic compounds

**Chemistry involved in the titrimetric exercises : **Acid – Base titrations, use of indicators, Redox titrations and their indicators

**Chemical principles involved in the qualitative salt analysis : **Cations – Pb2+, Cu2+, Al3+, Fe3+, Zn2+, Ni2+, Ca2+, Ba2+, Mg2+, NH4+; Anions – CO32−, S2−, SO42−, NO3−, NO2−, Cl−, Br− and I−.

## MU OET Biology Syllabus 2018

**Manipal University Biology Syllabus 2018**

**GENERAL BIOLOGY TOPICS**

**Biosystematics :** Introduction – Need, history and types of classification ( Artificial, Natural and Phylogenetic ) , Species concept, Binomial nomenclature with examples, Rules and advantages of binomial nomenclature. Linnaean hierarchy – Kingdom to species with examples ( Cocos nucifera and Homo sapiens ). The five – kingdom system of classification in detail – General characters of kingdoms Monera, Protista, Mycota, Metaphyta and Metazoa.

**Cell Biology : Cell structure **

Structure and functions of cell components – cell wall, plasma membrane ( fluid mosaic model ), endoplasmic reticulum, plastids ( brief ), mitochondria ( brief ), Golgi complex, Ribosomes, Lysosomes, Centrosome, vacuole and nucleus – nuclear envelope ( nuclear pores and nuclear lamina ) nucleoplasm, nucleolus and chromatin. A brief account of ergastic substances ( mention about reserve food, secretory and excretory substances with examples ). Differences between plant cell and animal cell.

**Chromosomes :** Discovery, shape, size and number of chromosomes, Autosomes and allosomes; Karyotype and idiogram. Chemical composition and function. General structure – Concept of centromere ( primary constriction ), secondary constriction, satellite, kinetochore, telomere. Types of chromosomes based on the position of centromere. Ultrastructural organization of the eukaryotic chromosome – nucleosome model. Numerical aspects of chromosomes: A brief note on aneuploidy ( monosomy and trisomy ) and euploidy ( haploidy, diploidy and polyploidy ).

**Cell Reproduction :** Cell division and types. Concept of cell cycle. Mitotic division and significance.

Meiotic division and its significance. Cancer – meaning of cancer, benign and malignant tumours, characters of cancer cells, types of cancer ( Carcinoma, Sarcoma, Lymphoma and Leukemia ), causes of cancer ( physical, chemical and biological carcinogens with examples ). Concept of cell senescence and apoptosis ( programmed cell death ).

**BOTANY TOPICS**

**Diversity of life on earth :** Kingdom Monera and other simple living forms – Prions and Viroids : Concept of prions and viroids – definition, discovery, chemical nature with one example of disease each – Creutzfeldt – Jacob disease ( CJD ) and Potato spindle tuber disease ( PSTV ).

**Viruses :** Introduction – living and non – living properties of viruses. Types of viruses – Plant viruses, Animal viruses, Bacterial viruses, DNA viruses and RNA viruses (Only definitions with examples to include the following – Viral disease in plants – Tobacco Mosaic, Cauliflower Mosaic, Potato Mottle, Leaf Mosaic of tomato and Banana Bunchy Top; viral diseases in animals-Rabies, Dog distemper, Viral diseases in man-Japanese Encephalitis, Poliomyelitis, Hepatitis-B, Herpes, AIDS and Conjunctivitis). Structure of T4 Bacteriophage, multiplication of T4 phage ( Lytic cycle only ).

**Bacteria :** Introduction. Classification of bacteria based on mode of nutrition ( Heterotrophic bacteria – parasitic, saprophytic and sumbiotic – and Autotrophic bacteria – photosynthetic and chemosynthetic; definition and one example for each group ). Ultrastructure of the bacterial cell. Reproduction in bacteria – asexual reproduction by binary fission, endospore formation and sexual mechanism ( genetic recombination in bacteria – transduction, transformation and conjugation with details of HFR conjugation only ). Importance of bacteria (i) Beneficial aspects – Scavenging, Fermentation, Retting, Antibiotics, Ecological importance, Importance in Genetic engineering and Importance in mineral extraction. (ii) Harmful aspects (iii) Food spoilage and food poisoning. Bacterial diseases – Brief and introductory information on the following diseases : Citrus canker, Anthrax, Cholera, Gastric ulcer, Tuberculosis and Syphilis ( details of treatment are not required ). (iv) A brief introduction on Archaea and their importance.

**Cyanobacteria :** Introduction. Structure and reproduction of Nostoc. Differences between bacteria and Cyanobacteria. Importance of Cyanobacteria.

**Kingdom Protista :** General characters. Mentioning the following divisions with suitable examples –

Chrysophyta ( Diatoms ), Euglenophyta ( Euglena ) and Protozoa. Taxonomic position of Algae with reference to the five-kingdom classification choosing the following examples : Desmids ( typical members of Protista ) and Spirogyra ( A member of metaphyta ) are both included in division Chlorophyta ( Green Algae ). Importance of Algae ( in brief ).

**Kingdom Mycota :** The Fungi : General characters of Fungi. Mentioning divisions with suitable examples. Zygomycota – Rhizopus : Ascomycota – Saccharomyces; Basidiomycota – Agaricus; Duteromycota – Cercospora. Importance of Fungi; A brief account of mushroom culturing ( paddy straw mushroom culturing ).

**Kingdom Metaphyta :** Bryophyta : General characters of Bryophytes. Mentioning classes with suitable examples – Hepaticopsida – Riccia; Anthocerotopsida – Anthoceros; Bryopsida – Funaria.

**Pteridophyta :** General characters of Pteridophytes. Mentioning classes with suitable examples – Psilotopsida – Psilotum; Lycopsida – Selaginella; Sphenopsida – Equisetum; Pteropsida – Nephrolepis.

**Gymnosperms :** General characters of Gymnosperms. Mentioning classes with suitable examples – Cycadopsida – Cycas; Coniferopsida – Pinus; Gnetopsida – Gnetum.

**Angiosperms :** General characters of angiosperms – Typical dicotyledonous and monocotyledonous plants ( Brassica and brass ) and difference between dicotyledons and monocotyledons. Study of the Angiosperm flower. Technical terms used in description of flower – Actinomorphic, Zygomorphic, Unisexual, Bisexual, Pedicellate, Sessile, Bracteate, Ebracteate, Homochlamydeous, Heterochlamydeous. Complete flower, Incomplete flower, Epigynous, Hypogynous and Perigynous flowers.

**The parts of the flower**

**a) Accessory whorls**

- Concept of perianth
- Calyx – polysepalous and gamosepalous condition with one example each.
- Corolla – Polypetalous and Gamopetalous condition.
- Aestivation – definition and types – Valvate, Imbricate and Twisted types with one example each.

**b) Essential whorls**

- Androecium – parts of a stamen, adelphy, syngeny, synandry and epipetaly. Anther lobes – monothecous and dithecous conditions with one example each.
- Gynoecium – part of gynoecium, concept of carpel, Types of gynoecium – apocarpous and syncarpous gynoecium. Types of gynoecium based on number of carpels – monocarpellary, bicarpellary, tricarpellary and multicarpellary conditions. Nature of ovary of gynoecium with reference to locule – unilocular, bilocular, trilocular and multilocular conditions. Placentation – definition, types – marginal, axile, basal and parietal.

**International structure of essential parts :** a) T.S of mature anther and structure of the pollen grain ( Microsporogenesis not needed ) b) Structure of a mature anatropous ovule ( Megasporogenesis not needed ).

**Pollination in Angiosperms :** Definition, self and cross pollination, types ( Autogamy, Allogamy, Geitonogamy, Xenogamy, Cleistogamy, Homogamy ). Agents ( Anemophily, Zoophily – Entomophily – Ornithophily and Hydrophily ) with examples. ( Pollination mechanisms not needed ).

**Fertilization in Angiosperms :** Definition, a brief account of double fertilization and its significance ( Embryogeny not required ).

**The Angiosperm fruit :** Definition, types of fruits – Simple fruits – fleshy fruits ( drupe and berry ), Dry fruits ( capsule, cypsela and cremocarp ) and Pome ( apple ). Aggregate fruits – etaerio of follicles. Multi fruits – Scrosis.

**The Angiosperm seed :** Concept of seed. A typical dicotyledonous seed ( Example: Bean seed ). A typical monocotyledonous seed ( Example : Maize grain ).

**Taxonomy and Economic Botany :** Taxonomy: An outline of classification system of Engler and Prantl. Distinguishing characters and plants of economic interest of the following families of angiosperms :

Malvaceae – ( Hibiscus, Cotton, Lady’s finger ).

Apocynaceae – ( Catheranthus roseus, Rauwolfia serpentiana, Plumeria alba and Nerium indicum )

Musaceae – ( Musa paradisiaca and Ravenala madagascariensis ).

**Economic Botany :** Introduction. Oil yielding plants – Groundnut and Sunflower. Cereals and millets – Rice and Jowar. Pulses – Pigeon pea and Bengal gram. Medicinal plants – Adathoda vasica, Ephedra gerardiana, Dryopteris, Santalum album, Gymnema sylvestre, Ocimum sanctum, Phyllanthus emblica. Spices – Pepper, cloves and cardamom. Beverages – Coffee, cocoa and tea. ( Mentioning scientific names, family, parts used and uses only ).

**Elements of plant pathology : Symptoms, etiology, type and nature of pathogens, and methods of control with reference to the following diseases :**

- Banana bunchy top
- Tikka disease of groundnut
- Crown gall ( of any common dicot plant ).

**GENERAL BIOLOGY TOPICS**

**Introduction to Biology :** Definition of Biology and its main branches – Botany and Zoology. Scope of Biology. Branches of Biology ( definition only ). Classical branches – morphology, cytology, histology, anatomy, physiology, developmental biology, biosystamatics, genetics, ecology, organic evolution and palaeontology. Interdisciplinary branches – biophysics, biochemistry and biostatistics. Applied branches and career prospects – agriculture, entomology,silviculture, pathology, apiculture, microbiology and bioinformatics. Role of biology in dispelling myths and disbeliefs.

**Biomolecules : Carbohydrates :** Definition. Classification – monosaccharides ( ribose, deoxyribose, glucose, fructose and galactose ), oligosaccharides ( maltose, sucrose and lactose ) and polysaccharides ( starch, glycogen, cellulose, pectin, chitin and agar agar ). Biological significance.

**Proteins :** Definition. Classification – simple proteins ( albumins, globulins, histones, actin, myosin and keratin ), conjugate proteins – Chromoproteins ( haemoglobin ), glycoproteins ( mucin of saliva ), phospoproteins ( casein of milk ) and lipoproteins ( lipovitelline of egg yolk ). Biological significance of amino acid and proteins.

**Lipids :** Definition. Classification – Simple lipids – oils ( vegetable oil and oil of animal origin ), fats ( butter ) and waxes (beeswax), Compound lipids – phospholipids ( lecithin and cephalin ) and sphingolipids ( cerebrosides ), Related compounds – steroids ( estrogen, progesterone and testosterone ), sterols ( cholesterol ) and prostaglandins. Biological significance.

**Enzymes :** Definition, properties, classification based on functions. Mode of action – induced fit theory of Koshland.

**Nucleic acid :** Occurrence, basic chemical composition ( nucleoside and nucleotide ), mention of type ( DNA and RNA ) and functions ( structural details are not required ). [ ***Note :** Details of chemical structure of biomolecules are not required ].

**Origin of life and organic evolution : Origin of life :** Introduction. Concept of abiogenesis and biogenesis ( experimental evidences not required ). A.I.Oparin’s Theory of chemical evolution of life (Views of Haldane and Sidney Fox to be mentioned ). Stanley Miller’s experiment in support of chemical evolution.

**Organic evolution :** Introduction. Darwin’s Theory ( DDT resistance in mosquitoes and industrial melanism in Peppered moth, to illustrate natural selection to be quoted as examples ). Brief account of Mutation Theory. Neo Darwininism – Introduction, Darwinian concept vs Neo Darwinian concept ( gene pool and gene frequency ), Hardy – Weinberg Law and sources of variations as evolutionary force – sexual reproduction, genetic drift, gene flow, mutation and isolation ( reproductive and geographic ).

**ZOOLOGY TOPICS**

**Diversity of animal life :** Introduction. Outline classification of kingdom Animalia ( only the major phyla to be considered ). Major animal phyla: Outline classification as treated in ‘A Manual of Zoology’ Vol. I and Vol. II (1971) by Ekambarantha Ayyar. Non-chordata ( animals without backbone ) – General characters and classification up to classes ( salient features of classes of Invertebrate phyla not to be given ) with suitable examples of the following phyla: Protozoa, Porifera, Coelenterata, Platyhelminthes, Nematoda, Annelida, Arthropoda, Mollusca and Echinodermata. Chordata (Animals with backbone ) – Fundamental characters and classification of chordata up to subphyla – Hemichordata, Urochordata, Cephalochordata and Vertebrata with suitable examples. Subphylum Vertebrata – Salient features with examples of (i) Subphylum Pisces : Class Chondreichthyes and Class Osteichthyes ); (ii) Superclass Tetrapoda: Amphibia, Reptilia, Aves and Mammalia. Differences between non-chordates and chordates.

**Study of Morphology :** Cockroach – Periplaneta sp. Morphology ( Structure of head capsule and compound eye not required ). Digestive and nervous systems.

**Animal resources :** Sericulture; Definition. Main aspects – moriculture, rearing of silkworms and reeling.

**Brief account of moriculture :** definition, methods ( row and pit systems ) and its importance. Types of silk – mulberry and non – mulberry ( Tasar, Eri and Muga ). Diseases of mulberry silkworm – Pebrine, Muscardine or Calcino, Flacherie and Grasserie ( Listing of diseases and causative organisms only ).

**Aquaculture :** Definition. Areas – fin fisheries and shell fisheries. Pisciculture: definition, capture fisheries and culture fisheries. Inland fisheries – procedure. Monoculture, monosex culture and polyculture (composite fish farming) – meaning with examples.

**Dairy :** Definition. Types of indigenous cattle with examples based on utility – draught, milching and dual purpose ( Cow breeds – Sindhi, Sahiwal, Amrithmahal, Hallikar, Ongole and Haryana; Buffalo breeds – Murrah, Surti, Mehsana and Nagpuri ). Examples of high yielding exotic breeds ( Holstein, Red Dane, Jersey and Brown Swiss ). Nutritive value of milk. Utility of cattle – biogas, leather, gelatin and organic manure.

**Poultry :** Definition. Types of indigenous fowls with examples based on utility – layers, broilers and dual purpose ( Aseel, Chittagong, Ghagus, Basra and Kadaknath ). Examples of exotic breeds ( White Leghorn, Cornish, Rhode Island Red Plymouth Rock and Newhampshire ). Giriraj – origin and salient features.

Nutritive value of egg. Diseases ( Respiratory mycoplasmosis, Fowl pox candidiasis, Raniketh and Fowl cholera) – Mentioning of diseases and causative organisms only.

**Vermiculture :** Definition and procedure. Vermicompost – degradation of organic wastes and role of Earthworm in soil fertility.

**BIOLOGY – II**

**GENERAL BIOLOGY TOPICS**

**Molecular Biology : ** Nucleic acids : DNA – Occurrence, DNA as the genetic material ( with the experiment of Avery as evidence ), chemical composition, structure ( Watson – Crick model ), Semiconservative method of replication. RNA – Occurrence, chemical composition, brief account of structure and functions of genetic RNA, rRNA, mRNA and tRNA ( clover – leaf model ).

**Gene :** The gene, the genetic code and genetic control of protein synthesis – Concept of gene ( prokaryotic and eukaryotic ), genetic code and its characteristics, genetic control of protein synthesis ( transcription and translation ) and Lac operon concept.

**Biotechnology :** Introduction : Scope of biotechnology.

**Genetic Engineering :** Introduction; Tools used in genetic engineering – Vectors ( plasmid – pUC18 ), Enzymes ( REN and Ligase ), Host cell ( E.coli ) and Bioreactors.

Recombinant DNA technology and its applications : Insulin synthesis to be used as an example.

**A brief account of :** DNA fingerprinting, Gene therapy, Human genome project, Monoclonal antibodies.

Improvement of crop plants : Breeding techniques; Tissue culture technique – organ culture example: stem; transgenic plants example: Golden rice.

**Improvement of animals :** Breeding techniques and stem cell culture, transgenic animals example : Cattle. Hazards and safeguards of genetic engineering.

**BOTANY TOPICS**

**Plant history & anatomy :** Introduction: Definition and general classification of plant tissues.

**Meristems :** Definition, structure and classification based on position, origin and function ( theories an apical organization not required ).

Permanent Tissues – Distribution, structure and functions of: Simple tissues: Parenchyma ( Chorenchyma and Aerenhyma ), Collenchyma ( angular, lacunar & lamellar ) and Sclerenchyma – Fibres ( Intraxylary and Extraxylary ), Sclereids ( Macrosclereids, Brachysclereids, Astrosclereids and Osteosclereids ).

Complex tissues: Xylem and Phloem. Definition of the terms: Primary and secondary vascular tissues, exarch xylem, endarch xylem, collateral conjoint open and collateral conjoint closed vascular bundles, radial arrangement of vascular tissues. Secondary growth in dicot stem: intrastelar and extrastelar secondary growth. Anatomy of different parts of flowering plant.

**Water relations of plants :** Fundamental concepts: Importance of water to plants. Significance and definitions of the following: Imbibition, Diffusion, Osmosis, Endosmosis, Exosmosis, Plasmolysis, Deplasmolysis, Turgor pressure, Well pressure, Osmotic pressure. Water potential and its components.

Absorption of water: Structure of root hair. Sources of water for plants ( available water and nonavailable water ). Region of absorption of water in plants. Entry of water from soil into xylem of root. Active and passive absorption of water ( active absorption to show osmotic and non-osmotic processes ).

Ascent of sap: Definition and evidences to show the involvement of xylem (the Balsam plant experiment). Composition of xylem sap. Transpiration pull theory – merits and demerits.

**Loss of water in plants :** Transpiration – Definition and types. Structure of a typical stomatal apparatus ( dicot example only ). Mechanism of stomatal movement – Steward’s Starch hydrolysis theory and K+ pump theory. Factors influencing the rate of transpiration ( external ). Significance of transpiration. A brief note on antitranspirants.

**Guttation :** A brief account of guttation – occurrence, causes and structure of hydathode.

**Translocation of solutes :** Definition and evidences in support of involvement of phloem in the process ( Girdling experiment and Tracer method ). Composition of phloem sap. Munch’s mass flow hypothesis with merits and demerits. Vein loading.

**Bioenergetics : Introduction :** Light as the source of energy and ATP as energy currency.

**Photosynthesis :** Definition. Ultrastructure of the chloroplast. Photosynthetic pigments and their role; composition of photsystems I & II. ( Molecular structures and formulae not required ). Mechanism – light reaction – cyclic and noncyclic photophosprylations; Dark reaction ( C3 pathway – Calvin cycle ) – ( details of regeneration steps not required ); C4 pathway and CAM ( definition and examples only ). Influence of external factors on photosynthesis; Blackman’s law of limiting factors. Significance of photosynthesis.

**Respiration :** Definition and types ( aerobic and anaerobic ). Ultra structure of mitochondrion. Mechanism of aerobic respiration – Glycolysis, Krebs cycle and Terminal oxidation. Anaerobic respiration – Mechanism of fermentation in the presence of yeast and lactic acid bacteria. Role of external factors, respiratory quotient (RQ) and its significance and Pasteur effect.

**Growth and growth regulators in plants : Growth :** Definition, regions of growth, phases of growth and growth curve.

**Growth regulators : Definition. Role of the following plant hormones ( Details of experiments on discovery of hormones not required ) : **

- Auxins.
- Gibberellins.
- Cytokinins.
- Abscissic acid.
- Ethylene.

Synthetic growth regulators and their applications ( with reference to IAA, IBA, NAA, 2, 4-D, BAP and Ethephon ).

**GENERAL BIOLOGY TOPICS**

**Genetics :** Mendelian genetics: Mendel and his work. Definitions of the following terms: Allele, Phenotype, Genotype, Homozygous and Heterozygous. Principles of inheritance: Unit characters, dominance, law of segregation ( purity of gametes ) and law of independent assortment. Monohybrid cross, Dilhybrid cross and Test cross.

**Deviations from Mendelian laws :** Incomplete dominance: Example – Flower colour in Mirabilis jalapa.

**Multiple allelism :** Example – ABO blood groups and their inheritance in man: Blood typing; Rh factor with a note on erythroblastosis foetalis. Sex linked inheritance in man: Example – Inheritance of colour-blindness and hypertrichosis in man.

**Genetic disorders in man :** Chromosomal disorders – Down’s syndrome, Klinefelter’s syndrome, Turner’s syndrome and Cri-du-Chat syndrome. Gene disorders – Sickle cell anaemia, haemophilia.

**Biodiversity : Definition and Types :** Ecosystem or habitat diversity, Species diversity and Genetic diversity.

**Biodiversity profiles of India and Karnataka :** Species diversity, Endemic species, Threatened species and Endangered species.

**Benefits of biodiversity :** Economic – Traditional crop varieties and lesser known plants and animals of food value, medicinal plants harvested from wild habitat. Ecological / Social – For controlling soil – water regimes and hydrology, for efficient organic residue management and soil fertility management. Ethical – Cultural, Spiritual and Religious belief systems centred around the concept of sacred species, sacred groves and sacred landscapes.

**Biodiversity depletion :** Anthropocentric causes – urbanization, expansion of agriculture, deforestation, pollution, acidification of soil and water, mining activities, desertification and loss of soil fertility. Intellectual property rights: Patenting life forms.

**Concept of ecosystem sustainability :** Conservation of natural resources based on traditional ecological knowledge ( TEK) : Conservation of Water – rainwater harvesting and watershed management. Conservation of soil – Prevention of soil erosion and maintenance of soil fertility: methods of soil conservation. Conservation of forests – Afforestation and maintenance of biosphere reserves. Conservation of wild life – (i) Setting up of national parks, sanctuaries, bioreserves and zoos (ii) Habitat improvement.

**Global issues :** Concept, causes, effects and control measures of the following: Global warming and greenhouse effect, Ozone layer depletion, Acid rain, Nuclear winter.

**BOTANY TOPICS**

**Man in health and diseases :** Concept of Homeostasis – The central Dogma in physiology: Definition. Meaning of internal environment. Factors to be kept constant to achieve homeostasis. An example to illustrate homeostasis – regulation of blood glucose level by liver and pancreas through negative feedback. A note on diabetes mellitus.

**Body defence and immunity :** Introduction. Nonspecific body defences : a) Surface barriers b) Cellular and bio-chemical defences: phagocytosis, natural killer cells, interferons and inflammatory response. Specific body defences ( immunity ): Antigen and antibody, role of B and T lymphocytes. Types of immunity: Active ( infection and vaccination ) and Passive ( from mother and immune serum Y-globulins ).

**Digestion :** Gross anatomy of human digestive system ( structure of tooth not required ). Components of food ( concept of balanced diet ). Physiology of digestion of carbohydrates, proteins and fats. Disorders: Causes, symptoms and prevention of hyperacidity and ulcer, jaundice and its types and hepatitis.

**Circulation :** Introduction. Gross anatomy of the human heart. Mechanism of working of heart – cardiac cycle, stroke volume, cardiac out-put, complete double circulation. Origin and conduction of heart beat. Mechanism of blood clotting ( Best and Taylor theory ). Blood pressure – hypotension and hypertension. Disorders – causes and symptoms of myocardial infarction and cyanosis.

**Respiration : Gross anatomy of human respiratory system. Mechanism of respiration :**

- Breathing ( inspiration and expiration )
- External respiration ( exchange of oxygen and carbon dioxide between alveoli and blood )
- Internal respiration ( exchange of oxygen and carbon dioxide between blood and body cells )
- Cellular respiration. Disorders : Rhinitis, Asthma and bronchogenic carcinoma. Artificial breathing.

**Excretion :** Introduction. Gross structure of nephron, Physiology of urine formation. Chemical composition of urine. Disorders: a. Renal failure – acute and chronic b. Renal calculi. Kidney replacement therapy: a brief note on dialysis ( haemodialysis and continuous ambulatory peritoneal dialysis ) and kidney transplantation.

**Nervous system :** Components – CNS, PNS & ANS. Human brain – structure ( sagittal section only ) and functions ( functional areas of cerebrum not required ). Human spinal cord – structure and functions. Meaning of reflex arc and reflex action. A brief study of the endocrine functions of the pituitary. Disorders: Meaning, causes and symptoms of epilepsy, Parkinson’s disease, Alzheimer’s disease and Huntington’s chorea. Alcoholism and its effects. Narcotic drugs – meaning, listing of types ( stimulants, depressants, analgesics and hallucinogens ) and their effects. Drug abuse and addiction, Efforts to counter alcoholism and drug menace.

**Continuity of life :** Developmental biology ( basics of sexual reproduction ) – Gametogenesis: Spermatogenesis – formation of spermatids and spermiogenesis ( details of spermiogenesis are not required ). Ultrastructure of human sperm. Oogenesis. Generalized structure of ovum.

Fertilization – Definition. Types – external and internal. Mechanism. Significance.

Early development of frog – Structure of egg. Cleavage. Blastulation. Gastrulation. Derivatives of primary germ layers.

Human Reproduction: A brief account of Fertilization, Implantation, Placenta. Role of gonadotropins and sex hormones in males and females ( meaning of menstrual cycle to be highlighted ).

Fertility control – Need for fertility control. Survey of family planning methods: Spacing methods ( Barriers, IUDs, Hormonal and Physiological ) and Terminal methods ( Tubectomy and Vasectomy ).

Infertility control – Meaning and causes of infertility in males and females. Remedical methods ( Assisted conception methods ) – IVF,ET,GIFT and ZIET. ( details of GIFT AND ZIFT not required ).

Sexually transmitted diseases – Meaning, causative organisms, mode of infection, symptoms and preventive measures of gonorrhoea, syphilis and AIDS.

## MU OET Mathematics Syllabus 2018

**Manipal University Mathematics Syllabus 2018**

**SETS, RELATIONS AND FUNCTIONS**

**Sets :** Sets and their representations. Empty set. Finite and Infinite sets. Equal sets. Subsets. Subsets of the set of real numbers especially intervals (with notations). Power set. Universal set. Venn diagrams. Union and intersection of sets. Difference of sets. Complement of a set, Properties of Complement sets.

**Relations and functions :** Ordered pairs, Cartesian product of sets. Number of elements in the Cartesian product of two finite sets. Cartesian product of the reals with itself (upto R × R × R).

Definition of relation, pictorial diagrams, domain, co-domain and range of a relation. Function as a special kind of relation from one set to another. Pictorial representation of a function, domain, co-domain and range of a function. Real valued function of the real variable, domain and range of these functions, constant, identity, polynomial, rational, modulus, signum and greatest integer functions with their graphs. Sum, difference, product and quotients of functions

Relations and functions : Types of relations: Reflexive, symmetric, transitive and equivalence relations. One to one and onto functions, composite functions, inverse of a function. Binary operations.Partial fractions, Logarithms and its related properties.

Trigonometric functions: Positive and negative angles. Measuring angles in radians and in degrees and conversion from one measure to another. Definition of trigonometric functions with the help of unit circle. Truth of the identity sin 2x + cos2x x = 1 , for all x. Signs of trigonometric functions and sketch of their graphs. Expressing sin ( x+y ) and cos ( x+y ) in terms of sin x, sin y, cos x and cos y. Deducing the identities like following

Identities related to sin 2x ,cos2x , tan 2x ,sin3x ,cos3x and tan3x. General solution of trigonometric equations of the type sinθ= sinα , cosθ = cosα and tanθ = tanα. Proofs and simple applications of sine and cosine formulae.

Inverse trigonometric functions: Definition, range, domain, principal value branches. Graphs of inverse trigonometric functions. Elementary properties of inverse trigonometric functions.

**ALGEBRA**

**Principle of mathematical induction :** Process of the proof by induction, motivating the application of the method by looking at natural numbers as the least inductive subset of real numbers. The principle of mathematical induction and simple applications.

**Complex numbers and quadratic equations :** Introduction, Complex numbers, Algebra of complex numbers, Brief description of algebraic properties of complex numbers, The modulus and the conjugate of complex number, Argand plane and polar representation, Fundamental theorem of algebra. Solution of quadratic equations in the complex number system, Square root of a complex number.

**Linear inequalities :** Linear inequalities, Algebraic solutions of linear inequalities in one variable and their representation on the number line. Graphical solution of linear inequalities in two variables. Solution of system of linear inequalities in two variables – graphically.

**Permutations and combinations :** Fundamental principle of counting. Factorial n. Permutations and combinations derivation of formulae and their connections, simple applications.

**Binomial theorem :** History, statement and proof of the binomial theorem for positive integral indices. Pascal’s triangle, general and middle term in binomial expansion, simple applications.

**Sequence and series :** Sequence and Series. Arithmetic Progression (A.P.), Arithmetic Mean (A.M.), Geometric Progression (G.P.), general term of a G.P., sum of n terms of a G.P. Arithmetic and geometric series, infinite G.P. and its sum, geometric mean (G.M.). Relation between A.M. and G.M. Sumto n terms of the special series

**Matrices :** Concept, notation, order, equality, types of matrices, zero matrix, transpose of a matrix, symmetric and skew symmetric matrices. Addition, multiplication and scalar multiplication of matrices, simple properties of addition, multiplication and scalar multiplication. Non-commutativity of multiplication of matrices and existence of non-zero matrices whose product is the zero matrix (restrict to square matrices of order 2). Concept of elementary row and column operations. Invertible matrices and proof of the uniqueness of inverse, if it exists; (Here all matrices will have real entries).

**Determinants :** Determinant of a square matrix (up to 3 × 3 matrices), properties of determinants, minors, cofactors and applications of determinants in finding the area of a triangle. Adjoint and inverse of a square matrix. Consistency, inconsistency and number of solutions of system of linear equations by examples, solving system of linear equations in two or three variables (having unique solution) using inverse of a matrix.

**COORDINATE GEOMETRY, VECTORS AND THREE-DIMENSIONAL GEOMETRY**

**Straight lines :** Brief recall of 2-D from earlier classes, shifting of origin. Slope of a line and angle between two lines. Various forms of equations of a line : parallel to axes, point-slope form, slope-intercept form, twopoint form, intercepts form and normal form. General equation of a line. Equation of family of lines passing through the point of intersection of two lines. Distance of a point from a line.

**Conic sections :** Sections of a cone: Circles, ellipse, parabola, hyperbola, a point, a straight line and pair of intersecting lines as a degenerated case of a conic section. Standard equations and simple properties of parabola, ellipse and hyperbola. Standard equation of a circle.

**Vectors :** Vectors and scalars, magnitude and direction of a vector. Direction cosines /ratios of vectors. Types of vectors (equal, unit, zero, parallel and collinear vectors), position vector of a point, negative of a vector, components of a vector, addition of vectors, multiplication of a vector by a scalar, position vector of a point dividing a line segment in a given ratio. Scalar (dot) product of vectors, projection of a vector on a line. Vector

(cross) product of vectors, scalar triple product.

**Three-dimensional geometry :** Coordinate axes and coordinate planes in three dimensions. Coordinates of a point. Distance between two points and section formula. Direction cosines /ratios of a line joining two points. Cartesian and vector equation of a line, coplanar and skew lines, shortest distance between two lines. Cartesian and vector equation of a plane. Angle between (i) two lines, (ii) two planes, (iii) a line and a plane. Distance of a point from a plane.

**CALCULUS**

**Limits and derivatives :** Derivatives introduced as rate of change both as that of distance function and

geometrically. Intuitive idea of limit

of derivative, relate it to slope of tangent of the curve, derivative of sum, difference, product and quotient of functions. Derivatives of polynomial of trigonometric functions

**Continuity and differentiability :** Continuity and differentiability, derivative of composite functions, chain rule, derivatives of inverse trigonometric functions, derivative of implicit function. Concepts of exponential, logarithmic functions. Derivatives of log_{e} z and z^{e} . Logarithmic differentiation. Derivative of functions expressed in parametric forms. Second order derivatives. Rolle’s and Lagrange’s Mean Value Theorems

(without proof) and their geometric interpretations.

**Applications of derivatives :** Applications of derivatives: Rate of change, increasing / decreasing functions, tangents and normal, approximation, maxima and minima ( first derivative test motivated geometrically and second derivative test given as a provable tool ). Simple problems (that illustrate basic principles and understanding of the subject as well as real-life situations ).

**Integrals :** Integration as inverse process of differentiation. Integration of a variety of functions by substitution, by partial fractions and by parts, only simple integrals of the type

to be evaluated.

Definite integrals as a limit of a sum. Fundamental Theorem of Calculus (without proof). Basic properties of definite integrals and evaluation of definite integrals.

**Applications of the integrals :** Applications in finding the area under simple curves, especially lines, arcs of circles / parabolas / ellipses ( in standard form only ), area between the two above said curves ( the region should be clearly identifiable ).

**Differential equations :** Definition, order and degree, general and particular solutions of a differential equation. Formation of differential equation whose general solution is given. Solution of differential equations by method of separation of variables, homogeneous differential equations of first order and first degree. Solutions of linear differential equation of the type –

**dy /****dx + Py = Q** where and are functions of x or constant

**dx /****dy + Px = Q** where and are functions of y or constant

**MATHEMATICAL REASONING**

Mathematically acceptable statements. Connecting words/phrases – consolidating the understanding of “if and only if (necessary and sufficient) condition”, “implies”, “and/or”, “implied by”, “and”, “or”, “there exists” and their use through variety of examples related to real life and Mathematics. Validating the statements involving the connecting words – difference between contradiction, converse and contrapositive.

**STATISTICS AND PROBABILITY**

**Statistics :** Measure of dispersion; mean deviation, variance and standard deviation of ungrouped/grouped data. Analysis of frequency distributions with equal means but different variances.

**Probability :** Random experiments: outcomes, sample spaces (set representation). Events: Occurrence of events, ‘not’, ‘and’ & ‘or’ events, exhaustive events, mutually exclusive events. Axiomatic (set theoretic) probability, connections with the theories of earlier classes. Probability of an event, probability of ‘not’, ‘and’, & ‘or’ events.Multiplications theorem on probability. Conditional probability, independent events, total probability, Baye’s theorem. Random variable and its probability distribution, mean and variance of haphazard variable. Repeated independent ( Bernoulli ) trials and Binomial distribution.

**LINEAR PROGRAMMING**

Introduction, related terminology such as constraints, objective function, optimization, different types of linear programming ( L.P. ) problems, mathematical formulation of L.P. problems, graphical method of solution for problems in two variables, feasible and infeasible regions, feasible and infeasible solutions, optimal feasiblesolutions ( up to three non-trivial constrains ).

## MU OET English Syllabus 2018

**Manipal University General English Syllabus 2018**

The test of English Language for the entrance examination covers ‘General English’ of the 10 + 2 standard. It is not designed to evaluate students’ knowledge of English literature, but to test their ability to grasp the fundamental concepts in English grammar and usage. Proficiency in English language is tested through objective-type multiple-choice questions on grammar, vocabulary, sentence correction, synonyms, antonyms, homophones, homonyms, one word substitutions, idioms and phrases, phrasal verbs, and usage. Students are not required to learn the glossary of complicated grammatical jargon, but should have the basic knowledge of word usage, matching of subject and verbs, correct usage of tenses, and grammatically correct sentences acceptable in standard written communication.

The syllabus will include the following areas

- Tense – Use of proper tense and sequence of tense
- Modals (have to/had to, must, should, need, ought to and their negative forms)
- Subject – verb concord
- Pronouns
- Sentence structure
- Usages in English
- Commands and requests
- Statements
- Questions

- Clauses
- Noun clauses
- Adverb clauses of condition and time
- Relative clause

- Determiners/ Use of proper articles
- Prepositions
- Vocabulary
- Synonyms
- Antonyms
- Spel

to get top mark in manipal mbbs entrance 2015 which book should i refer????